Fundamentals of Biochemistry




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BIOCHEMISTRY 241(CRN 31188)

Fundamentals of Biochemistry


Course Syllabus and Schedule

Fall 2005
Instructor. Dr. Harry Davis, office in Kokio 116, office phone is 734-9186 and messages may be left on the answering machine. email harryd@hawaii.edu
Kapi’olani Community College is an Equal Opportunity/Affirmative Action Institution. If you have a disability and have not voluntarily disclosed the nature of your disability and the support you need, you are invited to contact the Special Student Services Office, 734-9552 (V/TTY), Ilima 105, for assistance.
Class. MWF from 9:00 - 9:50 AM in Kokio 107
Office Hours. Please feel free to get help from me during office hours, by appointment, or anytime I am not in lecture. I will leave a note on the door if I must attend a meeting instead.

MWF 8:00 - 8:50 AM, 11:00 - 11:55 AM

MW 2:30 PM – 3:00 PM

You may also see me during the following scheduled lab if I am not giving a lecture or a review

F 1:00 - 5:00 PM in Kokio 109
The Purpose of Biochemistry 241. Biochemistry 241 is the first semester of a two-semester survey of general chemistry, organic chemistry, and biochemistry designed for the allied health professions. The second semester is Biochemistry 244 at KCC or 341 at Manoa. These are not lab courses. These two courses can be taken in order to complete the one-year chemistry requirement for majors in the School of Nursing at the Manoa campus. Biochemistry 241 satisfies the Diversification Requirement in the Natural Sciences (Physical science, DP) for a Bachelors Degree.
Course Competencies. Competencies are listed in the KCC general catalog.
Prerequisites. Algebra (Math 25) is a prerequisite. Since chemistry is a quantitative science, the ability to solve mathematical problems is very important in order to learn chemistry. The math required to understand a chemical concept will be covered along with the concept. You may ask the instructor for extra help during office hours, or you can borrow materials that may help you.
Course Materials.

1) "Fundamentals of General, Organic, and Biological Chemistry", 6th edition, by John R. Holum (1998). The study guide is optional

2) a basic scientific calculator (less than $20)

3) a periodic table ($0.25 at the bookstore)


Course Structure. The course is composed of four units. There will be assigned homework problems. Answers to all problems in the book and appropriate resource materials will be placed in the Health and Natural Sciences Learning Resource Center located in Kokio 202. Check your hawaii.edu email account as some materials may be emailed to you (attached is an instruction sheet on how to forward your email to another account).

You will be given an exam on the material covered in each of the first three units as they are completed. The final exam will cover the entire course with an emphasis on unit four. Homework will count for 10% of your grade. These will be designed so that you will know what to expect for the exams. Exams are the most important part of your grade since they are worth 90% of your grade. You should do homework problems with the intent of learning how to do similar problems on the exam.


Grading. How well one does on an exam is relative and a poor performance on one exam does not necessarily reflect what you have learned. Therefore, your lowest exam on the first three units will be counted only half as much as the other exams. The final exam will not be affected. The grading scale will be based on the following
90-100 % A / 80-89 % B / 70-79 % C / 50-69 % D / 0-50 % F
October 31 is the last day for withdrawal from the course. After this date a W can be assigned only by the Dean of Students for a certified medical reason or for a death in the immediate family. A form requesting the incomplete grade can only be filed by students who are close to completing the course with a passing grade. Disappearing without officially withdrawing from the course will result in assignment of an F by the administration.
Missing an exam can have serious consequences. Do not wait until after the exam is given to try to make up an exam. If you know that you have a scheduling conflict you must make arrangements with the Instructor prior to the exam. In the case of an unexpected illness or problem you must still notify there Instructor before the exam is given and be prepared to present a doctors note or similar evidence to provide a valid excuse. You might not receive full credit for a make up exam.
Student Responsibility. The job of the Instructor is to provide the best possible presentation of the material that he can, and to provide the best learning environment that is possible. It is not the Instructor's job to make a student study nor to accommodate the student by lowering the standards so that a student can pass. It is the student's responsibility to put forth the effort required to learn the material and to become competent with it. This means doing lots of problems and using good study habits. I will be happy to help you obtain these goals. Do not waste time trying to lower the standards of the course because these are in congruence with the UH system as well as with the American Chemical Society and the International Union of Pure and Applied Chemistry. The student should not burden the Instructor with scheduling problems and special requirements. This distracts from the experience of all other students as well as the Instructor. The student should:
1. preview the lecture material before coming to class

2. attend every class and take notes for later review

3. bring the text to class to follow the lecture

4. do problems from the text until you are competent - the first step to learning is to find out

what you don't know

5. make a list of what you don't understand and bring it to class and /or office hours

6. realize that this is a skills building course and so will require a lot of study outside of class

7. get help as soon as you need it, don't procrastinate


Study Groups. Participation in a study group is the best way to learn chemistry- to learn by helping each other. Please get to know each other and form study groups. Students from study groups outperform others.
What is Chemistry ? Chemistry is the study of how matter and energy behave. It is also a scientific method for observing the world and all of life. Knowledge of chemistry is used to make new discoveries about the world (research) and to change some aspects of the world by the invention of new materials and methods (technology). Chemistry is used by most other scientific disciplines making it a basic or universal science. There are hundreds of different fields and sub fields of chemistry with very specific journals dedicated to each. Finally, chemistry is a practical science that can be applied in every day life. For example, you use chemistry when you clean your house and when you read the food labels in the grocery store.
What is Organic Chemistry ? Organic chemistry is the study of the chemical and physical properties of organic compounds. Organic compounds are those which contain carbon and represent over 95% of known compounds. Some organic chemists isolate new compounds from natural sources and determine the structural formulas. These new compounds may have important pharmacological functions such as anti-cancer drugs. Others try to synthesize compounds that have known structures and which are difficult or expensive to obtain from natural sources. Other organic chemists try to determine how organic compounds react so that we can gain a greater ability to synthesize compounds that we may want in the future. Most of the materials that you are touching are man-made organic compounds.
What is Biochemistry ? Biochemistry is the application of chemical principles to biology. Science has progressed to the point that almost every type of biological research requires some aspect of chemistry and you will find that biochemistry covers a very wide range of subjects. Biochemists are usually involved in what is called basic research, for example in the search for the exact cause of cancer. Fewer biochemists are involved in applied research, for example the testing of a particular drug in cancer patients for the remission of cancer. Biochemists would be involved in the development of the drug rather than its clinical trials.

Biochemistry starts with the study of the chemical and biological properties of the molecules that make up living organisms. It then progresses to how these properties function in the organism. Diseases and malfunctions are then studied on the molecular level, that is, how the diseased molecules are different, why they become different, and what can be done to prevent them from becoming different.


very Tentative Lecture Schedule
week 1 chapter Topics

M Aug 22 1 Introduction, Math Skills

W Aug 24 1 Goals, Methods, and Measurements

F Aug 26 1 Goals, Methods, and Measurements


week 2

M Aug 29 1 Goals, Methods, and Measurements

W Aug 31 2 Matter and Energy

F Sept 2 2 Matter and Energy


week 3

M Sept 5 - Labor Day Holiday

W Sept 7 2 Matter and Energy

F Sept 9 10 Radioactivity and Nuclear Chemistry


week 4

M Sept 12 10 Radioactivity and Nuclear Chemistry

W Sept 14 3 Atomic Theory and the Periodic Table

F Sept 16 3 Atomic Theory and the Periodic Table



week 5

M Sept 19 3 Atomic Theory and the Periodic Table

W Sept 21 - Exam 1

F Sept 23 4 Chemical Compounds and Chemical Bonds


week 6

M Sept 27 4 Chemical Compounds and Chemical Bonds

W Sept 29 4 Chemical Compounds and Chemical Bonds

F Oct 1 5 Quantitative Relationships in Chemical Reactions


week 7

M Oct 3 5 Quantitative Relationships in Chemical Reactions

W Oct 5 5 Quantitative Relationships in Chemical Reactions

F Oct 7 5 Quantitative Relationships in Chemical Reactions


week 8

M Oct 10 5 Quantitative Relationships in Chemical Reactions

W Oct 12 6 States of Matter and the Kinetic Theory

F Oct 14 6 States of Matter and the Kinetic Theory


week 9

M Oct 17 6 States of Matter and the Kinetic Theory

W Oct 19 - Exam 2

F Oct 21 6 States of Matter and the Kinetic Theory


week 10

M Oct 24 6 States of Matter and the Kinetic Theory

W Oct 26 7 Solutions and Colloids

F Oct 28 7 Solutions and Colloids


week 11

- October 31 is the last day to withdraw -

M Oct 31 7 Solutions and Colloids

W Nov 2 7 Solutions and Colloids

F Nov 4 7 Solutions and Colloids


week 12

M Nov 7 8 Acids, Bases, and Ionic Compounds

W Nov 9 8 Acids, Bases, and Ionic Compounds

F Nov 11 8 Acids, Bases, and Ionic Compounds


week 13

M Nov 14 8 Acids, Bases, and Ionic Compounds

W Nov 16 8 Acids, Bases, and Ionic Compounds

F Nov 18 - Exam 3




week 14

M Nov 21 9 Reaction Kinetics and Chemical Equilibria

W Nov 23 9 Reaction Kinetics and Chemical Equilibria

F Nov 25 - Thanksgiving Recess


week 15

M Nov 28 9 Reaction Kinetics and Chemical Equilibria

W Nov 30 9 Reaction Kinetics and Chemical Equilibria

F Dec 2 11 Organic Chemistry. Saturated Hydrocarbons


week 16

M Dec 5 11 Organic Chemistry. Saturated Hydrocarbons

W Dec 7 12 Organic Chemistry. Unsaturated Hydrocarbons

F Dec 9 - Finals begin


week 17

M Dec 12 - Final Exam 7:45 – 9:45 AM in the classroom


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